InSTAR Research
Translational Research is another vital component of InSTAR program. InSTAR team is involved in cutting-edge clinical and neurobiological research studies examining schizophrenia patients as well as unaffected first-degree relatives are facilitated through the Translational Psychiatry Laboratory (TransPsych Lab). The overarching focus of these studies is to evaluate the clinical implications as well as systems biology interactions in schizophrenia within the translational research paradigm.
Current studies at the TransPsych Lab attempt to evaluate composite biomarkers that underlie the neuroimmunological & neurotrophic aberrations reflective of neurodevelopmental pathogenesis in schizophrenia. These studies on Schizophrenia aim at integrating various endophenotypes with neurobiological parameters. Research techniques that we use include clinical / neurocognitive assessments, evaluation of markers of aberrant neurodevelopment like dermatoglyphics / digit ratio, brain imaging (structural MRI, functional MRI, DTI & MRS), eye tracking, EEG/ERP, tDCS, neurochemical & immunological assays, gene polymorphism & expression studies with specific focus on hippocampus abnormalities and its connectivity with several brain regions. These biological studies are complemented by psycho-social / psychological research assessments & intervention studies to facilitate holistic understanding & treatment for schizophrenia. An important component of these research studies examines the clinical utility of yoga therapy & its potential mechanistic basis in treatment of schizophrenia. These research studies are supported by Wellcome Trust / DBT India Alliance Senior Fellowship Research Grant, Innovative Young Biotechnologist Award as well as Centre of Excellence & Innovation in Biotechnology (CEIB) Programme Support from the Department of Biotechnology.
For further information please visit the website of TransPsych Lab
Current studies at the TransPsych Lab attempt to evaluate composite biomarkers that underlie the neuroimmunological & neurotrophic aberrations reflective of neurodevelopmental pathogenesis in schizophrenia. These studies on Schizophrenia aim at integrating various endophenotypes with neurobiological parameters. Research techniques that we use include clinical / neurocognitive assessments, evaluation of markers of aberrant neurodevelopment like dermatoglyphics / digit ratio, brain imaging (structural MRI, functional MRI, DTI & MRS), eye tracking, EEG/ERP, tDCS, neurochemical & immunological assays, gene polymorphism & expression studies with specific focus on hippocampus abnormalities and its connectivity with several brain regions. These biological studies are complemented by psycho-social / psychological research assessments & intervention studies to facilitate holistic understanding & treatment for schizophrenia. An important component of these research studies examines the clinical utility of yoga therapy & its potential mechanistic basis in treatment of schizophrenia. These research studies are supported by Wellcome Trust / DBT India Alliance Senior Fellowship Research Grant, Innovative Young Biotechnologist Award as well as Centre of Excellence & Innovation in Biotechnology (CEIB) Programme Support from the Department of Biotechnology.
For further information please visit the website of TransPsych Lab
